The Memory Keeper's Daughter

Memory keepers: a narrative study on siblings never known.

Drawing on literature relevant to the impact of sibling death, the authors examined the invisible loss of siblings never known. This article presents findings of a phenomenological study of 15 adult siblings who "storied" the psychological presence and power of a deceased infant sibling never known but who acted as memory keepers for their unknown sibling. Transcriptions of the 15 interviews we...

Boundary Keepers Takers

Time keepers abound

Time keepers abound very cell in the body has its own little clock, according to Emi Nagoshi, Ueli Schibler (University of Geneva, Switzerland), and colleagues. These peripheral clocks may be closely related to the body’s central clock—the suprachiasmatic nucleus (SCN). Neurons of the SCN maintain circadian gene expression for long periods of time. Other cells, however, were thought to rely on ...

Intracellular Gate-keepers of Tissue Glucocorticoid Action

L Chapman K, Holmes M, Seckl J. 11 -Hydroxysteroid Dehydrogenases: Intracellular Gate-Keepers of Tissue Glucocorticoid Action. Physiol Rev 93: 1139–1206, 2013; doi:10.1152/physrev.00020.2012.—Glucocorticoid action on target tissues is determined by the density of “nuclear” receptors and intracellular metabolism by the two isozymes of 11 -hydroxysteroid dehydrogenase (11 -HSD) which catalyze int...

Turning job finders into job keepers.

Most welfare-to-work programs designed to help single mothers leave welfare for employment focus on the challenge of finding a job. This article looks beyond the point of employment to consider the difficulty many former welfare recipients have keeping their jobs. The authors review evidence showing that many families cycle back and forth between welfare and work, losing jobs and returning to p...